Sanaz Memarzadeh

Positions

Professor of Obstetrics and Gynecology (tenured)
Professor of Molecular and Medical Pharmacology 
Director, G.O Discovery Lab 
UCLA Health Gynecologic Cancer Surgeon 
Gynecologic Cancer Surgeon West Los Angeles VA Hospital

Research Description 

Sanaz Memarzadeh is a surgeon-scientist and Professor at UCLA. She directs an independent highly energized research laboratory, the G.O. Discovery Laboratory, focused on advancing care and research for women impacted by gynecologic cancers. The goal at the G.O. Discovery Laboratory is to improve the way we treat patients with gynecologic cancers. As part of this goal, they are looking for effective and better tolerated therapies for these diseases, including ovarian cancer and endometrial cancers.

The GO discovery laboratory is funded by federal, state and philanthropic sources. 

The goals of the lab are:

• Explore unique cell types in ovarian and endometrial cancers causing relapse of disease and chemo resistance. 
• High throughput drug screening and testing drug combinations using disease in a dish model to overcome ovarian cancer platinum resistance. 
• Targeting therapy resistant ovarian cancers with cell-based immunotherapies using novel off the shelf immune cells such as iNKT and super charge NK cells.
• Development of physiologically relevant in vivo disease models with patient derived xenografts as a powerful platform for testing novel therapeutics. 
• Defining the cellular lineage and therapeutic targets in ovarian and uterine carcinosarcomas

Current Lab Members

• Laura James-Allan, Ph.D., Project Scientist, ljamesallan@mednet.ucla.edu
• Gabriella DiBernardo, Lab Manager, gdibernardo@mednet.ucla.edu
• Lauryn Ruegg, Staff Research Associate I, lruegg@mednet.ucla.edu
• Christopher Ochoa, Graduate Student, christopherochoa@mednet.ucla.edu